Her research stay at Fraunhofer CAT reflects the value of scientific exchange within the Fraunhofer network and contributes to Fraunhofer Spain’s objective of establishing collaborative research programmes with Fraunhofer Institutes.

During the exchange, Karnatz carried out experiments for her PhD project, which focuses on the analysis and investigation of a cell-derived matrix for the cultivation of brain cells. This work aims to support the establishment of cell models that more closely mimic the physiology of the brain, creating experimental conditions that can be used for compound testing in vitro before further assessment of their potential suitability for patients.

At Fraunhofer CAT, she used spinning disc confocal microscopy to observe where cells attach to the substrate and whether they express specific proteins related to migration and cell growth. This imaging capability provided detailed insight into cellular behaviour, supporting the evaluation of the matrix as a relevant environment for brain cell cultivation.

“I recommend this exchange not only for the scientific exchange itself, but also for the opportunity to work within an international team,” said Isabell Karnatz. 

The stay highlights how Fraunhofer CAT can support young researchers by providing access to specialised technological capabilities and applied biomedical research expertise. It also illustrates the practical value of collaboration between Fraunhofer Institutes, enabling complementary infrastructures and knowledge to be connected around specific scientific challenges.